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X-ray Crystallographic Structure of α-Helical Peptide Stabilized by Hydrocarbon Stapling at i,i + 1 Positions

Hydrocarbon stapling is a useful tool for stabilizing the secondary structure of peptides. Among several methods, hydrocarbon stapling at i,i + 1 positions was not extensively studied, and their secondary structures are not clarified. In this study, we investigate i,i + 1 hydrocarbon stapling betwee...

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Detalles Bibliográficos
Autores principales: Makura, Yui, Ueda, Atsushi, Kato, Takuma, Iyoshi, Akihiro, Higuchi, Mei, Doi, Mitsunobu, Tanaka, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160927/
https://www.ncbi.nlm.nih.gov/pubmed/34069753
http://dx.doi.org/10.3390/ijms22105364