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Efficacy and safety of oral tolvaptan in patients undergoing hemodialysis: a Phase 2, double-blind, randomized, placebo-controlled trial

BACKGROUND: Loop diuretics are used to manage fluid retention in patients with end-stage kidney disease undergoing hemodialysis (HD). This randomized, double-blind, placebo-controlled, Phase 2 trial evaluated the efficacy and safety of tolvaptan, a vasopressin V(2) receptor antagonist, in Japanese H...

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Detalles Bibliográficos
Autores principales: Ogata, Hiroaki, Shimofurutani, Naoko, Okada, Tadashi, Nagamoto, Hisashi, Akizawa, Tadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160953/
https://www.ncbi.nlm.nih.gov/pubmed/32901255
http://dx.doi.org/10.1093/ndt/gfaa148