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An Overview of the Relevance of IgG4 Antibodies in Allergic Disease with a Focus on Food Allergens

Antibodies of the IgG4 isotype are strongly associated with allergic disease but have several properties such as not precipitating with allergens, not activating complement and poor binding to Fcγ receptors that argue against a pro-inflammatory role. In keeping with that, IgG4 antibodies are a strik...

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Detalles Bibliográficos
Autores principales: Platts-Mills, Thomas A. E., Keshavarz, Behnam, Wilson, Jeffrey M., Li, Rung-chi, Heymann, Peter W., Gold, Diane R., McGowan, Emily C., Erwin, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160978/
https://www.ncbi.nlm.nih.gov/pubmed/34065166
http://dx.doi.org/10.3390/children8050418