CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation

Multisubunit cullin-RING ubiquitin ligase 4 (CRL4)-DCAF12 recognizes the C-terminal degron containing acidic amino acid residues. However, its physiological roles and substrates are largely unknown. Purification of CRL4-DCAF12 complexes revealed a wide range of potential substrates, including MOV10,...

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Detalles Bibliográficos
Autores principales: Lidak, Tomas, Baloghova, Nikol, Korinek, Vladimir, Sedlacek, Radislav, Balounova, Jana, Kasparek, Petr, Cermak, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161014/
https://www.ncbi.nlm.nih.gov/pubmed/34065512
http://dx.doi.org/10.3390/ijms22105394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161014/
https://www.ncbi.nlm.nih.gov/pubmed/34065512
http://dx.doi.org/10.3390/ijms22105394

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