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Comparative Transcriptomics of Immune Checkpoint Inhibitor Myocarditis Identifies Guanylate Binding Protein 5 and 6 Dysregulation

SIMPLE SUMMARY: Immune checkpoint inhibitors are revolutionizing cancer treatment, but lead to the occurrence of immune related adverse events including ICI-associated myocarditis (ICIM). To date, transcriptional alterations of this rare phenomenon with a high mortality rate are not characterized. 1...

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Detalles Bibliográficos
Autores principales: Finke, Daniel, Heckmann, Markus B., Salatzki, Janek, Riffel, Johannes, Herpel, Esther, Heinzerling, Lucie M., Meder, Benjamin, Völkers, Mirko, Müller, Oliver J., Frey, Norbert, Katus, Hugo A., Leuschner, Florian, Kaya, Ziya, Lehmann, Lorenz H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161064/
https://www.ncbi.nlm.nih.gov/pubmed/34065419
http://dx.doi.org/10.3390/cancers13102498