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Vitamin C Cytotoxicity and Its Effects in Redox Homeostasis and Energetic Metabolism in Papillary Thyroid Carcinoma Cell Lines

High-dose of vitamin C (L-ascorbic acid, ascorbate) exhibits anti-tumoral effects, primarily mediated by pro-oxidant mechanisms. This cytotoxic effect is thought to affect the reciprocal crosstalk between redox balance and cell metabolism in different cancer types. Vitamin C also inhibits the growth...

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Detalles Bibliográficos
Autores principales: Tronci, Laura, Serreli, Gabriele, Piras, Cristina, Frau, Daniela Virginia, Dettori, Tinuccia, Deiana, Monica, Murgia, Federica, Santoru, Maria Laura, Spada, Martina, Leoni, Vera Piera, Griffin, Julian Leether, Vanni, Roberta, Atzori, Luigi, Caria, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161084/
https://www.ncbi.nlm.nih.gov/pubmed/34065197
http://dx.doi.org/10.3390/antiox10050809