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Regulatory Noncoding and Predicted Pathogenic Coding Variants of CCR5 Predispose to Severe COVID-19

Genome-wide association studies (GWAS) found locus 3p21.31 associated with severe COVID-19. CCR5 resides at the same locus and, given its known biological role in other infection diseases, we investigated if common noncoding and rare coding variants, affecting CCR5, can predispose to severe COVID-19...

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Detalles Bibliográficos
Autores principales: Cantalupo, Sueva, Lasorsa, Vito Alessandro, Russo, Roberta, Andolfo, Immacolata, D’Alterio, Giuseppe, Rosato, Barbara Eleni, Frisso, Giulia, Abete, Pasquale, Cassese, Gian Marco, Servillo, Giuseppe, Gentile, Ivan, Piscopo, Carmelo, Della Monica, Matteo, Fiorentino, Giuseppe, Russo, Giuseppe, Cerino, Pellegrino, Buonerba, Carlo, Pierri, Biancamaria, Zollo, Massimo, Iolascon, Achille, Capasso, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161088/
https://www.ncbi.nlm.nih.gov/pubmed/34065289
http://dx.doi.org/10.3390/ijms22105372