Discovery of Novel eEF2K Inhibitors Using HTS Fingerprint Generated from Predicted Profiling of Compound-Protein Interactions

Background: Eukaryotic elongation factor 2 kinase (eEF2K) regulates the elongation stage of protein synthesis by phosphorylating eEF2, a process related to various diseases including cancer and cardiovascular and neurodegenerative diseases. In this study, we describe the identification of novel eEF2...

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Detalles Bibliográficos
Autores principales: Yoshimori, Atsushi, Kawasaki, Enzo, Murakami, Ryuta, Kanai, Chisato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161098/
https://www.ncbi.nlm.nih.gov/pubmed/34065377
http://dx.doi.org/10.3390/medicines8050023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161098/
https://www.ncbi.nlm.nih.gov/pubmed/34065377
http://dx.doi.org/10.3390/medicines8050023

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