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Targeting Mitochondrial Oncometabolites: A New Approach to Overcome Drug Resistance in Cancer

Drug resistance is the main obstacle for a successful cancer therapy. There are many mechanisms by which cancers avoid drug-mediated death, including alterations in cellular metabolism and apoptotic programs. Mitochondria represent the cell’s powerhouse and the connection between carbohydrate, lipid...

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Detalles Bibliográficos
Autores principales: Godel, Martina, Ortone, Giacomo, Anobile, Dario Pasquale, Pasino, Martina, Randazzo, Giulio, Riganti, Chiara, Kopecka, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161136/
https://www.ncbi.nlm.nih.gov/pubmed/34065551
http://dx.doi.org/10.3390/pharmaceutics13050762