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Targeting Mitochondrial Oncometabolites: A New Approach to Overcome Drug Resistance in Cancer
Drug resistance is the main obstacle for a successful cancer therapy. There are many mechanisms by which cancers avoid drug-mediated death, including alterations in cellular metabolism and apoptotic programs. Mitochondria represent the cell’s powerhouse and the connection between carbohydrate, lipid...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161136/ https://www.ncbi.nlm.nih.gov/pubmed/34065551 http://dx.doi.org/10.3390/pharmaceutics13050762 |