Comparing Predictions of a PBPK Model for Cyclosporine With Drug Levels From Therapeutic Drug Monitoring

This study compared simulations of a physiologically based pharmacokinetic (PBPK) model implemented for cyclosporine with drug levels from therapeutic drug monitoring to evaluate the predictive performance of a PBPK model in a clinical population. Based on a literature search model parameters were d...

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Detalles Bibliográficos
Autores principales: Zapke, Sonja E., Willmann, Stefan, Grebe, Scott-Oliver, Menke, Kristin, Thürmann, Petra A., Schmiedl, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161189/
https://www.ncbi.nlm.nih.gov/pubmed/34054518
http://dx.doi.org/10.3389/fphar.2021.630904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161189/
https://www.ncbi.nlm.nih.gov/pubmed/34054518
http://dx.doi.org/10.3389/fphar.2021.630904

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