A practical catalytic reductive amination of carboxylic acids

We report reductive alkylation reactions of amines using carboxylic acids as nominal electrophiles. The two-step reaction exploits the dual reactivity of phenylsilane and involves a silane-mediated amidation followed by a Zn(OAc)(2)-catalyzed amide reduction. The reaction is applicable to a wide ran...

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Detalles Bibliográficos
Autores principales: Stoll, Emma L., Tongue, Thomas, Andrews, Keith G., Valette, Damien, Hirst, David J., Denton, Ross M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161228/
https://www.ncbi.nlm.nih.gov/pubmed/34123174
http://dx.doi.org/10.1039/d0sc02271c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161228/
https://www.ncbi.nlm.nih.gov/pubmed/34123174
http://dx.doi.org/10.1039/d0sc02271c

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