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Hepatocyte Small Heterodimer Partner Mediates Sex-Specific Effects on Triglyceride Metabolism via Androgen Receptor in Male Mice

Mechanisms of sex differences in hypertriglyceridemia remain poorly understood. Small heterodimer partner (SHP) is a nuclear receptor that regulates bile acid, glucose, and lipid metabolism. SHP also regulates transcriptional activity of sex hormone receptors and may mediate sex differences in trigl...

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Detalles Bibliográficos
Autores principales: Palmisano, Brian T., Zhu, Lin, Litts, Bridget, Burman, Andreanna, Yu, Sophia, Neuman, Joshua C., Anozie, Uche, Luu, Thao N., Edington, Emery M., Stafford, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161262/
https://www.ncbi.nlm.nih.gov/pubmed/34065318
http://dx.doi.org/10.3390/metabo11050330