Mitochondrial Targeting Involving Cholesterol-Rich Lipid Rafts in the Mechanism of Action of the Antitumor Ether Lipid and Alkylphospholipid Analog Edelfosine

The ether lipid edelfosine induces apoptosis selectively in tumor cells and is the prototypic molecule of a family of synthetic antitumor compounds collectively known as alkylphospholipid analogs. Cumulative evidence shows that edelfosine interacts with cholesterol-rich lipid rafts, endoplasmic reti...

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Detalles Bibliográficos
Autores principales: Mollinedo, Faustino, Gajate, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161315/
https://www.ncbi.nlm.nih.gov/pubmed/34065546
http://dx.doi.org/10.3390/pharmaceutics13050763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161315/
https://www.ncbi.nlm.nih.gov/pubmed/34065546
http://dx.doi.org/10.3390/pharmaceutics13050763

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