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The Role of Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy

SIMPLE SUMMARY: Sphingolipids are membrane-associated lipids that are involved in signal transduction pathways regulating cell death, growth, and migration. In cancer cells, sphingolipids regulate pathways relevant to cancer therapy, such as invasion, metastasis, apoptosis, and lethal mitophagy. Not...

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Detalles Bibliográficos
Autores principales: Sheridan, Megan, Ogretmen, Besim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161379/
https://www.ncbi.nlm.nih.gov/pubmed/34069611
http://dx.doi.org/10.3390/cancers13102475