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Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion

The hard tick Ixodes ricinus is a vector of Lyme disease and tick-borne encephalitis. Host blood protein digestion, essential for tick development and reproduction, occurs in tick midgut digestive cells driven by cathepsin proteases. Little is known about the regulation of the digestive proteolytic...

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Detalles Bibliográficos
Autores principales: Kotál, Jan, Buša, Michal, Urbanová, Veronika, Řezáčová, Pavlína, Chmelař, Jindřich, Langhansová, Helena, Sojka, Daniel, Mareš, Michael, Kotsyfakis, Michail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161381/
https://www.ncbi.nlm.nih.gov/pubmed/34065290
http://dx.doi.org/10.3390/ijms22105371