Cyclin-Dependent Kinase Inhibitors in Hematological Malignancies—Current Understanding, (Pre-)Clinical Application and Promising Approaches

SIMPLE SUMMARY: Cyclin-dependent kinases are involved in the regulation of cancer-initiating processes like cell cycle progression, transcription, and DNA repair. In hematological neoplasms, these enzymes are often overexpressed, resulting in increased cell proliferation and cancer progression. Earl...

Descripción completa

Detalles Bibliográficos
Autores principales: Richter, Anna, Schoenwaelder, Nina, Sender, Sina, Junghanss, Christian, Maletzki, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161389/
https://www.ncbi.nlm.nih.gov/pubmed/34065376
http://dx.doi.org/10.3390/cancers13102497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161389/
https://www.ncbi.nlm.nih.gov/pubmed/34065376
http://dx.doi.org/10.3390/cancers13102497

Ejemplares similares