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Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A(2B) Receptor Binding Affinity
The G protein-coupled adenosine A(2B) receptor is suggested to be involved in various pathological processes accompanied by increased levels of adenosine as found in inflammation, hypoxia, and cancer. Therefore, the adenosine A(2B) receptor is currently in focus as a novel target for cancer therapy...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161391/ https://www.ncbi.nlm.nih.gov/pubmed/34069548 http://dx.doi.org/10.3390/ph14050485 |