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Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A(2B) Receptor Binding Affinity

The G protein-coupled adenosine A(2B) receptor is suggested to be involved in various pathological processes accompanied by increased levels of adenosine as found in inflammation, hypoxia, and cancer. Therefore, the adenosine A(2B) receptor is currently in focus as a novel target for cancer therapy...

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Detalles Bibliográficos
Autores principales:	Lindemann, Marcel, Dukic-Stefanovic, Sladjana, Hinz, Sonja, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Juhl, Cathleen, Steinbach, Jörg, Brust, Peter, Müller, Christa E., Wenzel, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161391/ https://www.ncbi.nlm.nih.gov/pubmed/34069548 http://dx.doi.org/10.3390/ph14050485

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