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Challenges in bioinformatics approaches to tumor mutation burden analysis

Several immune checkpoint inhibitors (ICIs) have already been introduced into clinical practice or are in advanced phases of clinical experimentation. Extensive efforts are being made to identify robust biomarkers to select patients who may benefit from treatment with ICIs. Tumor mutation burden (TM...

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Detalles Bibliográficos
Autores principales: Fenizia, Francesca, Pasquale, Raffaella, Abate, Riziero Esposito, Lambiase, Matilde, Roma, Cristin, Bergantino, Francesca, Chaudhury, Ruchi, Hyland, Fiona, Allen, Christopher, Normanno, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161416/
https://www.ncbi.nlm.nih.gov/pubmed/34084222
http://dx.doi.org/10.3892/ol.2021.12816