Cargando…

Sterol Sponge Mechanism Is Conserved for Glycosylated Polyene Macrolides

[Image: see text] Amphotericin-like glycosylated polyene macrolides (GPMs) are a clinically and industrially important family of natural products, but the mechanisms by which they exert their extraordinary biological activities have remained unclear for more than half a century. Amphotericin B exert...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Xiaorui, Zhang, Jiabao, Li, Xinyi, Xiao, Emily, Lange, Justin D., Rienstra, Chad M., Burke, Martin D., Mitchell, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161476/
https://www.ncbi.nlm.nih.gov/pubmed/34079896
http://dx.doi.org/10.1021/acscentsci.1c00148