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miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop

Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signaling, contributing to the development of glioma. However, the molecular mechanism of the int...

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Detalles Bibliográficos
Autores principales: Chen, Qiudan, Wang, Weifeng, Chen, Shuying, Chen, Xiaotong, Lin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161631/
https://www.ncbi.nlm.nih.gov/pubmed/34044759
http://dx.doi.org/10.1186/s11658-021-00266-9