Cargando…
miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop
Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signaling, contributing to the development of glioma. However, the molecular mechanism of the int...
Autores principales: | Chen, Qiudan, Wang, Weifeng, Chen, Shuying, Chen, Xiaotong, Lin, Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161631/ https://www.ncbi.nlm.nih.gov/pubmed/34044759 http://dx.doi.org/10.1186/s11658-021-00266-9 |
Ejemplares similares
-
Over-expression of lncRNA TMEM161B-AS1 promotes the malignant biological behavior of glioma cells and the resistance to temozolomide via up-regulating the expression of multiple ferroptosis-related genes by sponging hsa-miR-27a-3p
por: Chen, Qiudan, et al.
Publicado: (2021) -
Stress-specific response of the p53-Mdm2 feedback loop
por: Hunziker, Alexander, et al.
Publicado: (2010) -
MiR-181b sensitizes glioma cells to teniposide by targeting MDM2
por: Sun, Yan-chang, et al.
Publicado: (2014) -
mdm-miR828 Participates in the Feedback Loop to Regulate Anthocyanin Accumulation in Apple Peel
por: Zhang, Bo, et al.
Publicado: (2020) -
miR-29c contribute to glioma cells temozolomide sensitivity by targeting O(6)-methylguanine-DNA methyltransferases indirectly
por: Xiao, Songhua, et al.
Publicado: (2016)