Cytosine-5 methylation-directed construction of a Au nanoparticle-based nanosensor for simultaneous detection of multiple DNA methyltransferases at the single-molecule level

DNA methylation at cytosine/guanine dinucleotide islands (CpGIs) is the most prominent epigenetic modification in prokaryotic and eukaryotic genomes. DNA methyltransferases (MTases) are responsible for genomic methylation, and their aberrant activities are closely associated with various diseases in...

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Detalles Bibliográficos
Autores principales: Wang, Li-Juan, Han, Xiao, Qiu, Jian-Ge, Jiang, BingHua, Zhang, Chun-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161687/
https://www.ncbi.nlm.nih.gov/pubmed/34094232
http://dx.doi.org/10.1039/d0sc03240a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161687/
https://www.ncbi.nlm.nih.gov/pubmed/34094232
http://dx.doi.org/10.1039/d0sc03240a

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