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Increasing protein stability by engineering the n → π* interaction at the β-turn

Abundant n → π* interactions between adjacent backbone carbonyl groups, identified by statistical analysis of protein structures, are predicted to play an important role in dictating the structure of proteins. However, experimentally testing the prediction in proteins has been challenging due to the...

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Detalles Bibliográficos
Autores principales: Khatri, Bhavesh, Majumder, Puja, Nagesh, Jayashree, Penmatsa, Aravind, Chatterjee, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161691/
https://www.ncbi.nlm.nih.gov/pubmed/34094214
http://dx.doi.org/10.1039/d0sc03060k