Prognostic Impact of APOBEC3B Expression in Metastatic Urothelial Carcinoma and Its Association with Tumor-Infiltrating Cytotoxic T Cells

APOBEC3B enzymes are endogenous carcinogenic mutagens. Metastatic urothelial carcinomas often harbor APOBEC3B-mediated mutations in which tCw to T or G substitution occurs. Here, we evaluated patient survival and CD8+ T-cell density according to APOBEC3B expression in patients with metastatic urothe...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hyunho, Kim, Okran, Lee, Myung Ah, Lee, Ji Youl, Hong, Sung-Hoo, Ha, U-Syn, Yim, Kwangil, Kim, In-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161743/
https://www.ncbi.nlm.nih.gov/pubmed/33925044
http://dx.doi.org/10.3390/curroncol28030154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161743/
https://www.ncbi.nlm.nih.gov/pubmed/33925044
http://dx.doi.org/10.3390/curroncol28030154

Ejemplares similares