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A computational evaluation of targeted oxidation strategy (TOS) for potential inhibition of SARS-CoV-2 by disulfiram and analogues

In the new millennium, the outbreak of new coronavirus has happened three times: SARS-CoV, MERS-CoV, and SARS-CoV-2. Unfortunately, we still have no pharmaceutical weapons against the diseases caused by these viruses. The pandemic of SARS-CoV-2 reminds us the urgency to search new drugs with totally...

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Detalles Bibliográficos
Autores principales: Xu, Luyan, Tong, Jiahui, Wu, Yiran, Zhao, Suwen, Lin, Bo-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161800/
https://www.ncbi.nlm.nih.gov/pubmed/34089978
http://dx.doi.org/10.1016/j.bpc.2021.106610