The p70S6K/PI3K/MAPK feedback loop releases the inhibition effect of high-dose rapamycin on rat mesangial cell proliferation

Glomerular mesangial cell (MC) proliferation is one of the causative factors of glomerular diseases and one of their prominent pathological features. Rapamycin can inhibit MC proliferation and slow the progression to chronic renal fibrosis. The present study was designed to observe the role of rapam...

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Detalles Bibliográficos
Autores principales: Tian, Jihua, Chang, Sijia, Ji, He, Huang, Taiping, Guo, Haixiu, Kang, Jing, Wang, Yanhong, Zhou, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161859/
https://www.ncbi.nlm.nih.gov/pubmed/34034560
http://dx.doi.org/10.1177/20587384211000544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161859/
https://www.ncbi.nlm.nih.gov/pubmed/34034560
http://dx.doi.org/10.1177/20587384211000544

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