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A variant in TMPRSS2 is associated with decreased disease severity in COVID-19

BACKGROUND: Mortality due to COVID-19 caused by SARS-CoV-2 infection varies among populations. Functional relevance of genetic variations in Angiotensin-converting enzyme 2 (ACE2) and Transmembrane serine protease 2 (TMPRSS2), two crucial host factors for viral entry, might explain some of this vari...

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Detalles Bibliográficos
Autores principales: Ravikanth, Vishnubhotla, Sasikala, Mitnala, Naveen, Vankadari, Latha, Sabbu Sai, Parsa, Kishore Venkata Laxmi, Vijayasarathy, Ketavarapu, Amanchy, Ramars, Avanthi, Steffie, Govardhan, Bale, Rakesh, Kalapala, Kumari, Daram Sarala, Srikaran, Bojja, Rao, Guduru Venkat, Reddy, D. Nageshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161869/
https://www.ncbi.nlm.nih.gov/pubmed/34075330
http://dx.doi.org/10.1016/j.mgene.2021.100930