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An effective method to resolve ambiguous bisulfite-treated reads

BACKGROUND: The combination of the bisulfite treatment and the next-generation sequencing is an important method for methylation analysis, and aligning the bisulfite-treated reads (BS-reads) is the critical step for the downstream applications. As bisulfite treatment reduces the complexity of the se...

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Detalles Bibliográficos
Autores principales: Liu, Mengya, Xu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161933/
https://www.ncbi.nlm.nih.gov/pubmed/34044763
http://dx.doi.org/10.1186/s12859-021-04204-6