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An effective method to resolve ambiguous bisulfite-treated reads
BACKGROUND: The combination of the bisulfite treatment and the next-generation sequencing is an important method for methylation analysis, and aligning the bisulfite-treated reads (BS-reads) is the critical step for the downstream applications. As bisulfite treatment reduces the complexity of the se...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161933/ https://www.ncbi.nlm.nih.gov/pubmed/34044763 http://dx.doi.org/10.1186/s12859-021-04204-6 |