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Use of constitutive and inducible oncogene-containing iPSCs as surrogates for transgenic mice to study breast oncogenesis

BACKGROUND: Powerful constitutive and inducible transgenic / bitransgenic / tritransgenic murine models of breast cancer have been used over the past two decades to shed light on the molecular mechanisms by which the given transgenic oncogenes have interacted with other cellular genes and set in mot...

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Detalles Bibliográficos
Autores principales: Nguyen, Christine, Nguyen, Julie P. T., Modi, Arnav P., Ahmad, Ihsaan, Petrova, Sarah C., Ferrell, Stuart D., Wilhelm, Sabrina R., Ye, Yin, Schaue, Dorthe, Barsky, Sanford H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162012/
https://www.ncbi.nlm.nih.gov/pubmed/34044885
http://dx.doi.org/10.1186/s13287-021-02285-x