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Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance

Overcoming resistance to bioactive small molecules is a significant challenge for health care and agriculture. As a result, efforts to uncover the mechanisms of resistance are essential to the development of new antibiotics, anticancer drugs and pesticides. To study how nature evolves resistance to...

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Detalles Bibliográficos
Autores principales: Yan, Yan, Zang, Xin, Jamieson, Cooper S., Lin, Hsiao-Ching, Houk, K. N., Zhou, Jiahai, Tang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162069/
https://www.ncbi.nlm.nih.gov/pubmed/34094220
http://dx.doi.org/10.1039/d0sc03805a