Synthesis of pentasubstituted 2-aryl pyrroles from boryl and stannyl alkynes via one-pot sequential Ti-catalyzed [2 + 2 + 1] pyrrole synthesis/cross coupling reactions

Multisubstituted pyrroles are commonly found in many bioactive small molecule scaffolds, yet the synthesis of highly-substituted pyrrole cores remains challenging. Herein, we report an efficient catalytic synthesis of 2-heteroatom-substituted (9-BBN or SnR(3)) pyrroles via Ti-catalyzed [2 + 2 + 1] h...

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Detalles Bibliográficos
Autores principales: Cheng, Yukun, Klein, Channing K., Tonks, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162107/
https://www.ncbi.nlm.nih.gov/pubmed/34094289
http://dx.doi.org/10.1039/d0sc01576h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162107/
https://www.ncbi.nlm.nih.gov/pubmed/34094289
http://dx.doi.org/10.1039/d0sc01576h

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