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Diversity-oriented synthesis of peptide-boronic acids by a versatile building-block approach

A new strategy for the synthesis of peptide-boronic acids (PBAs) is presented. 20 Fmoc-protected natural amino acids with orthogonal side-chain protection were straightforwardly converted into their corresponding boron analogues in three simple steps. Subsequent immobilisation on commercially availa...

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Detalles Bibliográficos
Autores principales: Hinkes, Stefan P. A., Kämmerer, Severin, Klein, Christian D. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162117/
https://www.ncbi.nlm.nih.gov/pubmed/34094250
http://dx.doi.org/10.1039/d0sc03999c