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Heparin reversal by an oligoethylene glycol functionalized guanidinocalixarene

Unfractionated heparin (UFH), a naturally occurring anionic polysaccharide, is widely used as an anticoagulant agent in clinical practice. When overdosed or used in sensitive patients, UFH may cause various risks and a UFH neutralizer needs to be administered immediately to reverse heparinization. H...

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Detalles Bibliográficos
Autores principales: Huang, Qiaoxian, Zhao, Hong, Shui, Mingju, Guo, Dong-Sheng, Wang, Ruibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162181/
https://www.ncbi.nlm.nih.gov/pubmed/34094229
http://dx.doi.org/10.1039/d0sc03922e