Access to P-chiral sec- and tert-phosphine oxides enabled by Le-Phos-catalyzed asymmetric kinetic resolution

The synthesis of P-stereogenic building blocks is extremely difficult. Herein we report an efficient kinetic resolution of secondary phosphine oxides via a Le-Phos-catalyzed asymmetric allylation reaction with Morita–Baylis–Hillman carbonates. This method provides facile access to enantioenriched se...

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Detalles Bibliográficos
Autores principales: Qiu, Haile, Dai, Qiang, He, Jiafeng, Li, Wenbo, Zhang, Junliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162192/
https://www.ncbi.nlm.nih.gov/pubmed/34094261
http://dx.doi.org/10.1039/d0sc04041j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162192/
https://www.ncbi.nlm.nih.gov/pubmed/34094261
http://dx.doi.org/10.1039/d0sc04041j

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