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Total synthesis of dimeric Securinega alkaloids (−)-flueggenines D and I

We describe the total synthesis of (−)-flueggenines D and I. This features the first total synthesis of dimeric Securinega alkaloids with a C(α)–C(δ′) connectivity between two monomeric units. The key dimerization was enabled by a sequence that involves Stille reaction and conjugate reduction. The h...

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Detalles Bibliográficos
Autores principales: Jeon, Sangbin, Lee, Jinwoo, Park, Sangbin, Han, Sunkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162258/
https://www.ncbi.nlm.nih.gov/pubmed/34123190
http://dx.doi.org/10.1039/d0sc03057k