Cargando…

Total synthesis of dimeric Securinega alkaloids (−)-flueggenines D and I

We describe the total synthesis of (−)-flueggenines D and I. This features the first total synthesis of dimeric Securinega alkaloids with a C(α)–C(δ′) connectivity between two monomeric units. The key dimerization was enabled by a sequence that involves Stille reaction and conjugate reduction. The h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeon, Sangbin, Lee, Jinwoo, Park, Sangbin, Han, Sunkyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162258/ https://www.ncbi.nlm.nih.gov/pubmed/34123190 http://dx.doi.org/10.1039/d0sc03057k

Ejemplares similares

Collective total synthesis of C4-oxygenated securinine-type alkaloids via stereocontrolled diversifications on the piperidine core
por: Park, Sangbin, et al.
Publicado: (2022)

Total Synthesis of Dimeric HPI Alkaloids
por: Shen, Xianfu, et al.
Publicado: (2016)

Production of Therapeutically Relevant Indolizidine Alkaloids in Securinega suffruticosa In Vitro Shoots Maintained in Liquid Culture Systems
por: Raj, Danuta, et al.
Publicado: (2014)

Katupila (Securinega leucopyrus) as a potential option for diabetic wound management
por: Ajmeer, Ahamed Shahan, et al.
Publicado: (2014)

Unified total synthesis of the brevianamide alkaloids enabled by chemical investigations into their biosynthesis
por: Godfrey, Robert C., et al.
Publicado: (2021)

Possible roles of platelets in liver transplantation: regeneration and cancer recurrence
por: Han, Sangbin
Publicado: (2021)

Total synthesis of malagashanine: a chloroquine potentiating indole alkaloid with unusual stereochemistry
por: Kong, A., et al.
Publicado: (2017)

A short and efficient total synthesis of the bromotyrosine-derived alkaloid psammaplysene A
por: Xu, Jingjing, et al.
Publicado: (2018)

Management of Madhumehajanya Vrana (diabetic wound) with Katupila (Securinega leucopyrus [Willd] Muell.) Kalka
por: Ajmeer, Ahamed Shahan, et al.
Publicado: (2015)

Formal total synthesis of histrionicotoxin alkaloids via Hg(OTf)(2)-catalyzed cycloisomerization and SmI(2)-induced ring expansion
por: Matsumura, Kunihiro, et al.
Publicado: (2018)

Anti-Vascular Inflammatory Effect of Ethanol Extract from Securinega suffruticosa in Human Umbilical Vein Endothelial Cells
por: Han, Byung Hyuk, et al.
Publicado: (2020)

Dimeric Pimprinine Alkaloids From Soil-Derived Streptomyces sp. NEAU-C99
por: Yu, Zhiyin, et al.
Publicado: (2020)

Enantioselective total synthesis of (–)-colchicine, (+)-demecolcinone and metacolchicine: determination of the absolute configurations of the latter two alkaloids
por: Chen, Bo, et al.
Publicado: (2017)

Diversity and antimicrobial activity of endophytic fungi isolated from Securinega suffruticosa in the Yellow River Delta
por: Du, Wen, et al.
Publicado: (2020)

Annulation of O-silyl N,O-ketene acetals with alkynes for the synthesis of dihydropyridinones and its application in concise total synthesis of phenanthroindolizidine alkaloids
por: Lee, Seokwoo, et al.
Publicado: (2023)

Dimeric Cinchona alkaloids
por: Boratyński, Przemysław J.
Publicado: (2015)

The role of biocatalysis in the asymmetric synthesis of alkaloids
por: Schrittwieser, Joerg H., et al.
Publicado: (2013)

Corrigendum: Dimeric Pimprinine Alkaloids From Soil-Derived Streptomyces sp. NEAU-C99
por: Yu, Zhiyin, et al.
Publicado: (2020)

A Strategy for Complex Dimer Formation When Biomimicry Fails: Total Synthesis of Ten Coccinellid Alkaloids
por: Sherwood, Trevor C., et al.
Publicado: (2014)

Isolation of bergenin from the root bark of Securinega virosa and evaluation of its potential sleep promoting effect
por: Magaji, Mohammed Garba, et al.
Publicado: (2015)

Total synthesis of aristolactam alkaloids via synergistic C–H bond activation and dehydro-Diels–Alder reactions
por: Reddy, Mallu Chenna, et al.
Publicado: (2017)

Total synthesis of pyrano[3,2-e]indole alkaloid fontanesine B by a double cyclization strategy
por: Itoh, Tomoki, et al.
Publicado: (2019)

First total synthesis of ampullosine, a unique isoquinoline alkaloid isolated from Sepedonium ampullosporum, and of the related permethylampullosine
por: Vargas, Didier F., et al.
Publicado: (2019)

Total synthesis of the natural (−)-205B alkaloid and its activity toward α7 nAChRs
por: Mazeh, Sara, et al.
Publicado: (2022)

Isolation and total synthesis of dysidone A: a new piperidone alkaloid from the marine sponge Dysidea sp.
por: Lei, Yu, et al.
Publicado: (2023)

The role of biocatalysis in the asymmetric synthesis of alkaloids – an update
por: Cigan, Emmanuel, et al.
Publicado: (2021)

Unified approach to prenylated indole alkaloids: total syntheses of (–)-17-hydroxy-citrinalin B, (+)-stephacidin A, and (+)-notoamide I
por: Mercado-Marin, Eduardo V., et al.
Publicado: (2015)

Total synthesis of the indolizidine alkaloid tashiromine
por: Marsden, Stephen P, et al.
Publicado: (2008)

Total Synthesis of the Akuammiline Alkaloid Picrinine
por: Smith, Joel M., et al.
Publicado: (2014)

Total Synthesis of Alkaloid 205B
por: Tsukanov, Sergey V., et al.
Publicado: (2014)

Effects of the Proprioceptive Neuromuscular Facilitation Technique on Scapula Function in Office Workers with Scapula Dyskinesis
por: Hwang, Myeungsik, et al.
Publicado: (2021)

Synthesis and anticancer activity novel dimeric azatriperoxides
por: Makhmudiyarova, Nataliya N., et al.
Publicado: (2019)

Retraction: The synthesis and biological activity of marine alkaloid derivatives and analogues
por: Zhou, Shiyang, et al.
Publicado: (2021)

Synthesis of indole derivatives as prevalent moieties present in selected alkaloids
por: Heravi, Majid M., et al.
Publicado: (2021)

Alkylative Ring-Opening of Bicyclic Aziridinium Ion and Its Application for Alkaloid Synthesis
por: Yadav, Nagendra Nath, et al.
Publicado: (2019)

Antiprotozoal dimeric naphthylisoquinolines, mbandakamines B(3) and B(4), and related 5,8′-coupled monomeric alkaloids, ikelacongolines A–D, from a Congolese Ancistrocladus liana
por: Mufusama, Jean-Pierre, et al.
Publicado: (2019)

TfOH mediated intermolecular electrocyclization for the synthesis of pyrazolines and its application in alkaloid synthesis
por: Annes, Sesuraj Babiola, et al.
Publicado: (2018)

Finite element analyses of lateral condyle fracture fixation in paediatrics regarding configuration of Kirschner-wire
por: Jeon, Sangbin, et al.
Publicado: (2022)

Effects of Curved-Path Gait Training on Gait Ability in Middle-Aged Patients with Stroke: Protocol for a Randomized Controlled Trial
por: Jin, Youngmi, et al.
Publicado: (2023)

Total synthesis of the plant alkaloid racemic microthecaline A: first example of a natural product bearing a tricyclic quinoline-serrulatane scaffold
por: Penjarla, Thirupathi Reddy, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_36t707252cbbdhqu448e7mlm3b