Multiple reactivities of flavonoids towards pathological elements in Alzheimer's disease: structure–activity relationship

Amyloid-β (Aβ) accumulation, metal ion dyshomeostasis, oxidative stress, and cholinergic deficit are four major characteristics of Alzheimer's disease (AD). Herein, we report the reactivities of 12 flavonoids against four pathogenic elements of AD: metal-free and metal-bound Aβ, free radicals,...

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Detalles Bibliográficos
Autores principales: Nam, Geewoo, Hong, Mannkyu, Lee, Juri, Lee, Hyuck Jin, Ji, Yonghwan, Kang, Juhye, Baik, Mu-Hyun, Lim, Mi Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162271/
https://www.ncbi.nlm.nih.gov/pubmed/34094290
http://dx.doi.org/10.1039/d0sc02046j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162271/
https://www.ncbi.nlm.nih.gov/pubmed/34094290
http://dx.doi.org/10.1039/d0sc02046j

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