Competition between N and O: use of diazine N-oxides as a test case for the Marcus theory rationale for ambident reactivity

The preferred site of alkylation of diazine N-oxides by representative hard and soft alkylating agents was established conclusively using the (1)H–(15)N HMBC NMR technique in combination with other NMR spectroscopic methods. Alkylation of pyrazine N-oxides (1 and 2) occurs preferentially on nitrogen...

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Detalles Bibliográficos
Autores principales: Sheehy, Kevin J., Bateman, Lorraine M., Flosbach, Niko T., Breugst, Martin, Byrne, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162281/
https://www.ncbi.nlm.nih.gov/pubmed/34094230
http://dx.doi.org/10.1039/d0sc02834g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162281/
https://www.ncbi.nlm.nih.gov/pubmed/34094230
http://dx.doi.org/10.1039/d0sc02834g

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