Asymmetric synthesis of 1,2-fluorohydrin: iridium catalyzed hydrogenation of fluorinated allylic alcohol

We have developed a simple protocol for the preparation of 1,2-fluorohydrin by asymmetric hydrogenation of fluorinated allylic alcohols using an efficient azabicyclo thiazole-phosphine iridium complex. The iridium-catalyzed asymmetric synthesis of chiral 1,2-fluorohydrin molecules was carried out at...

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Detalles Bibliográficos
Autores principales: Ponra, Sudipta, Yang, Jianping, Wu, Haibo, Rabten, Wangchuk, Andersson, Pher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162319/
https://www.ncbi.nlm.nih.gov/pubmed/34094359
http://dx.doi.org/10.1039/d0sc04032k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162319/
https://www.ncbi.nlm.nih.gov/pubmed/34094359
http://dx.doi.org/10.1039/d0sc04032k

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