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Proteomimetic surface fragments distinguish targets by function

The fragment-centric design promises a means to develop complex xenobiotic protein surface mimetics, but it is challenging to find locally biomimetic structures. To address this issue, foldameric local surface mimetic (LSM) libraries were constructed. Protein affinity patterns, ligand promiscuity an...

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Detalles Bibliográficos
Autores principales: Tököli, Attila, Mag, Beáta, Bartus, Éva, Wéber, Edit, Szakonyi, Gerda, Simon, Márton A., Czibula, Ágnes, Monostori, Éva, Nyitray, László, Martinek, Tamás A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162404/
https://www.ncbi.nlm.nih.gov/pubmed/34094300
http://dx.doi.org/10.1039/d0sc03525d