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Bioorthogonal release of anticancer drugs via gold-triggered 2-alkynylbenzamide cyclization
Metal-based uncaging of biomolecules has become an emerging approach for in vivo applications, which is largely due to the advantageous bioorthogonality of abiotic transition metals. Adding to the library of metal-cleavable protecting groups, this work introduces the 2-alkynylbenzamide (Ayba) moiety...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162444/ https://www.ncbi.nlm.nih.gov/pubmed/34094342 http://dx.doi.org/10.1039/d0sc04329j |