Multimerized self-assembled caged two-in-one siRNA nanoparticles for photomodulation of RNAi-induced gene silencing

We rationally designed and developed caged siRNA nanoparticles (Multi-Chol-siRNA) self-assembled with cholesterol-modified multimerized caged siRNAs for photomodulation of siRNA gene silencing activity. Strong resistance to serum nuclease and RNase A was observed for these cholesterol-modified caged...

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Detalles Bibliográficos
Autores principales: Chen, Changmai, Jing, Nannan, Wang, Zhongyu, Zhang, Yu, Chen, Wei, Tang, Xinjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162473/
https://www.ncbi.nlm.nih.gov/pubmed/34094437
http://dx.doi.org/10.1039/d0sc03562a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162473/
https://www.ncbi.nlm.nih.gov/pubmed/34094437
http://dx.doi.org/10.1039/d0sc03562a

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