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Transient IL-33 upregulation in neonatal mouse lung promotes acute but not chronic type 2 immune responses induced by allergen later in life

Early life respiratory insults, such as viral infections or hyperoxia, often increase asthma susceptibility later in life. The mechanisms underlying this increased susceptibility are not fully understood. IL-33 has been shown to be critically involved in allergic airway diseases. IL-33 expression in...

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Detalles Bibliográficos
Autores principales: Iijima, Koji, Kobayashi, Takao, Matsumoto, Koji, Ohara, Kenzo, Kita, Hirohito, Drake, Li Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162637/
https://www.ncbi.nlm.nih.gov/pubmed/34048460
http://dx.doi.org/10.1371/journal.pone.0252199