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Site-selective aqueous C–H acylation of tyrosine-containing oligopeptides with aldehydes

The development of useful synthetic tools to label amino acids within a peptide framework for the ultimate modification of proteins in a late-stage fashion is a challenging task of utmost importance within chemical biology. Herein, we report the first Pd-catalyzed C–H acylation of a collection of Ty...

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Detalles Bibliográficos
Autores principales: San Segundo, Marcos, Correa, Arkaitz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162766/
https://www.ncbi.nlm.nih.gov/pubmed/34094398
http://dx.doi.org/10.1039/d0sc03791e