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2′-O-Trifluoromethylated RNA – a powerful modification for RNA chemistry and NMR spectroscopy

New RNA modifications are needed to advance our toolbox for targeted manipulation of RNA. In particular, the development of high-performance reporter groups facilitating spectroscopic analysis of RNA structure and dynamics, and of RNA–ligand interactions has attracted considerable interest. To this...

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Detalles Bibliográficos
Autores principales: Himmelstoß, Maximilian, Erharter, Kevin, Renard, Eva, Ennifar, Eric, Kreutz, Christoph, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162808/
https://www.ncbi.nlm.nih.gov/pubmed/34094374
http://dx.doi.org/10.1039/d0sc04520a