Mitohormesis reprograms macrophage metabolism to enforce tolerance

Macrophages generate mitochondrial reactive oxygen and electrophilic species (mtROS, mtRES) as antimicrobials during Toll-like receptor (TLR)-dependent inflammatory responses. Whether mitochondrial stress caused by these molecules impacts macrophage function is unknown. Here, we demonstrate that bot...

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Detalles Bibliográficos
Autores principales: Timblin, Greg A., Tharp, Kevin M., Ford, Breanna, Winchester, Janet M., Wang, Jerome, Zhu, Stella, Khan, Rida I., Louie, Shannon K., Iavarone, Anthony T., ten Hoeve, Johanna, Nomura, Daniel K., Stahl, Andreas, Saijo, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162914/
https://www.ncbi.nlm.nih.gov/pubmed/34031590
http://dx.doi.org/10.1038/s42255-021-00392-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162914/
https://www.ncbi.nlm.nih.gov/pubmed/34031590
http://dx.doi.org/10.1038/s42255-021-00392-w

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