Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst

Computational design of protein catalysts with enhanced stabilities for use in research and enzyme technologies is a challenging task. Using force-field calculations and phylogenetic analysis, we previously designed the haloalkane dehalogenase DhaA115 which contains 11 mutations that confer upon it...

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Detalles Bibliográficos
Autores principales: Markova, Klara, Chmelova, Klaudia, Marques, Sérgio M., Carpentier, Philippe, Bednar, David, Damborsky, Jiri, Marek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162949/
https://www.ncbi.nlm.nih.gov/pubmed/34094357
http://dx.doi.org/10.1039/d0sc03367g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162949/
https://www.ncbi.nlm.nih.gov/pubmed/34094357
http://dx.doi.org/10.1039/d0sc03367g

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