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Merging C(sp(3))–H activation with DNA-encoding

DNA-encoded library (DEL) technology has the potential to dramatically expedite hit identification in drug discovery owing to its ability to perform protein affinity selection with millions or billions of molecules in a few experiments. To expand the molecular diversity of DEL, it is critical to dev...

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Detalles Bibliográficos
Autores principales: Fan, Zhoulong, Zhao, Shuai, Liu, Tao, Shen, Peng-Xiang, Cui, Zi-Ning, Zhuang, Zhe, Shao, Qian, Chen, Jason S., Ratnayake, Anokha S., Flanagan, Mark E., Kölmel, Dominik K., Piotrowski, David W., Richardson, Paul, Yu, Jin-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162953/
https://www.ncbi.nlm.nih.gov/pubmed/34094436
http://dx.doi.org/10.1039/d0sc03935g