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Merging C(sp(3))–H activation with DNA-encoding
DNA-encoded library (DEL) technology has the potential to dramatically expedite hit identification in drug discovery owing to its ability to perform protein affinity selection with millions or billions of molecules in a few experiments. To expand the molecular diversity of DEL, it is critical to dev...
Autores principales: | Fan, Zhoulong, Zhao, Shuai, Liu, Tao, Shen, Peng-Xiang, Cui, Zi-Ning, Zhuang, Zhe, Shao, Qian, Chen, Jason S., Ratnayake, Anokha S., Flanagan, Mark E., Kölmel, Dominik K., Piotrowski, David W., Richardson, Paul, Yu, Jin-Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162953/ https://www.ncbi.nlm.nih.gov/pubmed/34094436 http://dx.doi.org/10.1039/d0sc03935g |
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